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Case report

Herpes zoster during pregnancy about one case report

Herpes zoster during pregnancy about one case report

Soumaya Kraiem1,&, Mahassen Ben Abdallah1, Khawla Moussa1, Hayet Laajili1


1Department of Gynecology Obstetric, University of Monastir, Maternity and Neonatology Center of Monastir, 5000 Monastir, Tunisia



&Corresponding author
Soumaya Kraiem, Department of Gynecology Obstetric, University of Monastir, Maternity and Neonatology Center of Monastir, 5000 Monastir, Tunisia




A lot of infectious diseases can occur in pregnancy. Their acquisition, clinical presentation, and course during gestation may be altered due to deficiency of the maternal cellular immunity. Herpes zoster, also known as shingles, (reactivation of varicella zoster virus) is one of the least infections which can be contracted by pregnant woman. But it does not present a big problem to mother or baby. The complications of zoster in pregnancy are no different from those in non-pregnant women.



Introduction    Down

Varicella zoster virus causes two different diseases, chickenpox (varicella) and shingles (herpes zoster). The relationship between these two diseases has been understood for more than 100 years and is based on this observation: Varicella zoster virus remains latent in human neurons for decades after varicella infection and sufficient varicella zoster virus -specific cellmediated immunity is necessary to maintain latency [1].



Patient and observation Up    Down

A 22 years old pregnant woman was admitted in our department for preterm premature rupture of membranes at 34 weeks of amenorrhea. She has a flare up of herpes zoster at the T10 to T11 dermatomes (Figure 1, Figure 2). She was treated symptomatically and rash disappeared after 2 weeks (Figure 3). Delivery was programmed at 37 weeks of amenorrhea to decrease risks of contamination of the newborn infant. The baby was healthy and he had not any rashes.



Discussion Up    Down

Following a primary infection with the varicella-zoster virus, the virus can remain latent in the dorsal root ganglia and might cause herpes zoster by reactivation. Clinically, herpes zoster causes contagious vesicular rashes, pain and itching in the dermatome distribution [2] and it is preceded in 80% cases by prodromal symptoms like pain and parasthesias [3]. With the exception of generalized herpes zoster, there is no viremia and usually no transplacental infection. The mother has neutralizing antibodies against varicella zoster virus which are passed on to the fetus through the placenta. Newborn infant possess specific maternal Ig G class antibodies and there is usually no longer viremic spread of varicella zoster virus [4]. A prospective study reported on 474 women diagnosed with herpes zoster during pregnancy. There were only 2 children with malformations, but no cases of congenital varicella syndrome among the live births and no serologic evidence of intrauterine infection [5]. There are no significant risks for the mother and infant associated with herpes zoster in pregnancy. Treatment of herpes zoster in imunocompetent pregnant women should be symptomatic; topical or systemic antiviral therapy is not recommended [6].



Conclusion Up    Down

Herpes zoster during pregnancy, unlike chickenpox, is not associated with increased risk of congenital malformations above the general population. Individuals with herpes zoster should cover their lesions in order to reduce the risk of transmitting varicella zoster virus to susceptible pregnant women.



Competing interests Up    Down

The authors declare no conflicts of interests.



Authors' contributions Up    Down

All the authors have read and agreed to the final manuscript.



Figures Up    Down

Figure 1: characteristic distribution of zoster

Figure 2: rash zoster

Figure 3: zoster rash after recovery



References Up    Down

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